Representative immunohistochemical staining of STC1 in LSCC.

<p>Positive immunostaining was observed in the cytoplasm and membranes of tumor cells. (A) Negative expression of STC1 in adjacent non-cancerous epithelial tissues. (B) High expression of STC1 in well-differentiated glottic LSCC. (C) Low expression of STC1 in poorly differentiated supraglottic LSCC. (D) Staining with negative control (phosphate-buffered saline) in LSCC specimens. (magnification 200×, scale bar = 50 µm).