Anesthesia with isoflurane reduces variability of data.

<p>Compared to MMF, isoflurane is able to reduce the variability of the results. Additionally, isoflurane at higher concentrations than commonly used might further reduce the variability of heart rate and heart rate dependent values such as cardiac output and cardiac index. However, compared with lower isoflurane concentrations (1.75%), high isoflurane concentrations (3%) show no significant cardiodepressive effects. A) Shows percentual standard deviations of single cycle values, and B) of mean values (average of 3 consecutive cycles). (C) Shows percentual standard deviations for cardiac output and cardiac index obtained with either MMF, 1.75% isoflurane or 3% isoflurane. D) Shows heart rate, E) cardiac output and F) cardiac index under different anesthetic regimens. EF = LVEF, EDV = end diastolic volume, ESV = end systolic volume, SV = stroke volume, HR = heart rate, CO = cardiac output, CI = cardiac index. 100 µl MMF: n = 6, 1.75% isoflurane and 3% isoflurane: n = 7. ***: p<0.001.