Voxelwise comparison between MS patients and healthy subjects.

<p>The axial, coronal and sagittal slices of (<b>a</b>)–(<b>d</b>) are shown in neurologic convention. Slices in (<b>a</b>) shows voxel-based t-tests, thresholded at the SVC significance level of 0.05, used to test if the ACMs of RR-MS patients are decreased relative to healthy subjects while (<b>b</b>) shows the corresponding, thresholded t-test based on FA. (<b>c</b>) and (<b>d</b>) shows the results of a similar comparison test between SP-MS patients and healthy subjects with the t-tests based on ACM depicted in (<b>c</b>) and the t-tests based on FA shown in (<b>d</b>). The background images shown are from the FMRIB58_FA atlas.