Peptide candidates possibly involved in HLA-B*58∶01 allogenicity.

<p>Peptide sequences were selected from the publication of Norcross et al, 2012 <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0095339#pone.0095339-Norcross1" target="_blank">[8]</a>. Peptides were considered only if they were eluted from cells treated with abacavir and were absent from abacavir untreated cells. IC50 values for HLA-B*57∶01 and HLA-B*58∶01 were calculated using the netMHC pan server <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0095339#pone.0095339-Hoof1" target="_blank">[12]</a>.</p>§<p>Peptide with Trp, Phe or Tyr at their C-term were excluded from the candidate list.</p>†<p>Name was given arbitrary with the letter of the first and the last residue of the peptide, followed by the number of amino acids.</p>‡<p>The ratio value corresponds to the IC50 for HLA-B*58∶01 divided by IC50 for HLA-B*57∶01. It may point to a difference of peptide affinity to both allotypes.