SH-11052 inhibits VEGF mediated Akt signaling.

<p>Phosphorylation of VEGFR2 (A) and Akt (C) was monitored in HRECs upon VEGF stimulation in the presence of varying concentrations of <b>2</b>. (B & D) Densitometry was performed using Quantity One software and analyzed using GraphPad Prism. The lines indicate the mean ± SEM of three biological replicates, * indicates <i>p</i><0.05 and ** indicates <i>p</i><0.01 compared to VEGF treatment alone (ANOVA with Dunnett's post hoc test).