Effects of high salt diet on blood pressure and left ventricle size in <i>sik2^+/+</i> and <i>sik2^−/−</i> mice.

<p>Black bars correspond to mice on normal salt diet, whereas blue bars correspond to mice on high salt diet. A) Body weight, B) Systolic blood pressure (SBP), C) Diastolic blood pressure (DBP) and D) Heart weight/body weight (HW/BW) ratio. E) Representative gross images of whole hearts, and F) Representative ultrasound scans. Quantitative analysis of G) left ventricular anterior wall (LVAW) thickness, H) left ventricular posterior wall (LVPW) thickness, I) Left ventricular end-diastolic diameter (LVDd) and J) Fractional shortening (FS). Mean ± s.e.m. of 7–9 mice in each group.