<p>Heat map denoting upregulated genes in red and down-regulated genes in green in <i>M. tb</i> grown in blood from 6 HIV- donors (1-6) and 6 HIV+ patients (7-12) with dye flip (12 samples for each condition, HIV- and HIV+). Genes are listed as upregulated or down-regulated in blood from both HIV- and HIV+ donors or in HIV- donor blood only or HIV+ patient blood only. HIV+ blood sample codes (H#) are listed at the bottom for comparison with CD4+ T cell counts and viral loads in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0094939#pone.0094939.s007" target="_blank">Table S1</a>.</p
<p>(<b>A</b>) Fold change scatterplot comparing gene expression between HIV T (+DC) (CD4<sup>+</sup>...
<div><p>Hematogenous dissemination of <i>Mycobacterium tuberculosis</i> (<i>M. tb</i>) occurs during...
The proportion of (a) CD3+ and (b) CD3+CD4+ lymphocytes expressing CD27, CD62L and CD38 as determine...
<p>(A) Heat map of <i>M. tb</i> genes upregulated ≥2 fold during replication in blood from HIV+ pati...
<p>(A) DosR regulon genes (B) Genes encoding heat shock proteins (8) and stimulators of heat shock p...
a<p>This study.</p>b<p>human differentiated THP-1cell line (THP-1)- (Fontan P et al., 2008) (110).</...
BACKGROUND: Transcriptomic host biomarkers could assist in developing effective diagnostics, vaccine...
a<p>Functional categories as designated in the Tuberculist website (<a href="http://tuberculist.epfl...
<p>(A) Upregulated genes arranged by functional category and corresponding blood environments. (B) D...
HIV-1 co-infection is a leading cause of susceptibility to tuberculosis (TB), with the risk of TB be...
<p>Log<sub>2</sub> fold-changes in expression of seven selected genes in <i>M. tb</i> replicating in...
<p>(A) Genes upregulated within ESX-1 locus. (B) Genes upregulated within ESX-5 locus. (C) Total gen...
<div><p>HIV replication is closely regulated by a complex pathway of host factors, many of them bein...
Previous studies of the effect of ART on gene expression in HIV-infected individuals have identified...
(A) Correlation heatmap representing DEGs in neutrophils from HCs, HIV patients with high and low CD...
<p>(<b>A</b>) Fold change scatterplot comparing gene expression between HIV T (+DC) (CD4<sup>+</sup>...
<div><p>Hematogenous dissemination of <i>Mycobacterium tuberculosis</i> (<i>M. tb</i>) occurs during...
The proportion of (a) CD3+ and (b) CD3+CD4+ lymphocytes expressing CD27, CD62L and CD38 as determine...
<p>(A) Heat map of <i>M. tb</i> genes upregulated ≥2 fold during replication in blood from HIV+ pati...
<p>(A) DosR regulon genes (B) Genes encoding heat shock proteins (8) and stimulators of heat shock p...
a<p>This study.</p>b<p>human differentiated THP-1cell line (THP-1)- (Fontan P et al., 2008) (110).</...
BACKGROUND: Transcriptomic host biomarkers could assist in developing effective diagnostics, vaccine...
a<p>Functional categories as designated in the Tuberculist website (<a href="http://tuberculist.epfl...
<p>(A) Upregulated genes arranged by functional category and corresponding blood environments. (B) D...
HIV-1 co-infection is a leading cause of susceptibility to tuberculosis (TB), with the risk of TB be...
<p>Log<sub>2</sub> fold-changes in expression of seven selected genes in <i>M. tb</i> replicating in...
<p>(A) Genes upregulated within ESX-1 locus. (B) Genes upregulated within ESX-5 locus. (C) Total gen...
<div><p>HIV replication is closely regulated by a complex pathway of host factors, many of them bein...
Previous studies of the effect of ART on gene expression in HIV-infected individuals have identified...
(A) Correlation heatmap representing DEGs in neutrophils from HCs, HIV patients with high and low CD...
<p>(<b>A</b>) Fold change scatterplot comparing gene expression between HIV T (+DC) (CD4<sup>+</sup>...
<div><p>Hematogenous dissemination of <i>Mycobacterium tuberculosis</i> (<i>M. tb</i>) occurs during...
The proportion of (a) CD3+ and (b) CD3+CD4+ lymphocytes expressing CD27, CD62L and CD38 as determine...