<p>PP2 (A) and compound 5 (B) are Src-family tyrosine kinases inhibitors, while CI-1040 (C) and PD 198306 (D) are MEK inhibitors.</p
ABSTRACT: Small molecules that inhibit the protein kinase A, G, and C (AGC) family of serine/threoni...
AbstractSome protein kinases are known to acquire resistance to selective small molecule inhibitors ...
<p>Eight chemical inhibitors were employed in this study. Depicted above are their chemical structur...
BackgroundSmall-molecule inhibitors that can target individual kinases are powerful tools for use in...
The aberrant activation of protein kinases is associated with many human diseases, most notably canc...
Copyright: © Yoshida et al. This is an open-access article distributed under the terms of the Creat...
<p>Molecular structures of the inhibitors: (A) PMI, (B) pDI, (C) WK23 and (D) WW8.</p
*S Supporting Information ABSTRACT: Selective inhibitors of individual subfamilies of G protein-coup...
A series of analogues of Amb639752, a novel diacylglycerol kinase (DGK) inhibitor recently discovere...
Protein kinases are key components in cellular signalling pathways as they carry out the phosphoryla...
<p>All are kinase inhibitors that were approved for clinical use at Nov. 2013.</p
Protein tyrosine kinases catalyze the transfer of phosphoryl groups from ATP to amino acids on prote...
<p>Twenty-eight PKD1 inhibitors were identified as primary hits in a screen using a radiometric PKD1...
The specificities of 65 compounds reported to be relatively specific inhibitors of protein kinases h...
Protein kinase D (PKD) is a family of serine/threonine kinases that has emerged as a novel therapeut...
ABSTRACT: Small molecules that inhibit the protein kinase A, G, and C (AGC) family of serine/threoni...
AbstractSome protein kinases are known to acquire resistance to selective small molecule inhibitors ...
<p>Eight chemical inhibitors were employed in this study. Depicted above are their chemical structur...
BackgroundSmall-molecule inhibitors that can target individual kinases are powerful tools for use in...
The aberrant activation of protein kinases is associated with many human diseases, most notably canc...
Copyright: © Yoshida et al. This is an open-access article distributed under the terms of the Creat...
<p>Molecular structures of the inhibitors: (A) PMI, (B) pDI, (C) WK23 and (D) WW8.</p
*S Supporting Information ABSTRACT: Selective inhibitors of individual subfamilies of G protein-coup...
A series of analogues of Amb639752, a novel diacylglycerol kinase (DGK) inhibitor recently discovere...
Protein kinases are key components in cellular signalling pathways as they carry out the phosphoryla...
<p>All are kinase inhibitors that were approved for clinical use at Nov. 2013.</p
Protein tyrosine kinases catalyze the transfer of phosphoryl groups from ATP to amino acids on prote...
<p>Twenty-eight PKD1 inhibitors were identified as primary hits in a screen using a radiometric PKD1...
The specificities of 65 compounds reported to be relatively specific inhibitors of protein kinases h...
Protein kinase D (PKD) is a family of serine/threonine kinases that has emerged as a novel therapeut...
ABSTRACT: Small molecules that inhibit the protein kinase A, G, and C (AGC) family of serine/threoni...
AbstractSome protein kinases are known to acquire resistance to selective small molecule inhibitors ...
<p>Eight chemical inhibitors were employed in this study. Depicted above are their chemical structur...
DOI
Add to ORKG