Gene-specific variation in DNA methylation before and after MOF supplementation.

<p>Box- and whisker plots represent DNA methylation as β-values (0CXCL12 (A), <i>SCRIB</i> (B), <i>PDGFRL</i> (C), <i>FERMT3</i> (D), <i>ICAM1</i> (E) and <i>VCAM1</i> (F). In <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0095527#pone-0095527-g008" target="_blank">figure 8A</a> CpG sites have been sorted according to their chromosome locus, including 5′-UTR, promoter (transcription start site region (TSS)), gene body and 3′-UTR region, as indicated in the figure. For <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0095527#pone-0095527-g008" target="_blank">figures 8B - F</a>, only the 5′-UTR promoter region (TSS) has been included. No significant MOF effects on DNA methylation β-values could be observed by one-way ANOVA and Bonferroni's post-hoc test.