Mutation of <i>pch-2</i> suppresses pairing defects in <i>syp-1</i> mutants.

<p>A. Meiotic nuclei in <i>syp-1</i> and <i>syp-1;pch-2</i> mutants stained with DAPI (blue) and antibodies against the <i>X</i> chromosome PC protein HIM-8 (red). B. Histogram representing the percentage of nuclei with paired HIM-8 signals as a function of germline position in wildtype (from <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1004291#pgen.1004291.s001" target="_blank">Figure S1A</a>), <i>syp-1</i>, <i>syp-1;pch-2</i>, and <i>syp-1;spo-11</i> mutants. C. Meiotic nuclei in <i>syp-1</i> and <i>syp-1;pch-2</i> mutants stained with DAPI (blue) and a FISH probe against the 5 s rDNA locus (red). D. Histogram representing the percentage of nuclei with paired FISH signals as a function of germline position in wildtype (from <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1004291#pgen.1004291.s001" target="_blank">Figure S1B</a>), <i>syp-1</i>, <i>syp-1;pch-2</i>, and <i>syp-1;spo-11</i> mutants. Error bars in both graphs indicate 95% confidence intervals. A * indicates a p value<0.05 and a ** indicates a p value of <0.0001. Significance was assessed by performing Fisher's exact test.