<p>Genotyping was performed as above using two reactions to distinguish between heterozygotes and Edn2KO mice. Lanes 1, 2, and 3 show Edn2+/?, Edn2KO, and WT mice that were genotyped from a single litter, respectively. Ovaries were collected from 23 to 31 day-old Edn2KO (n = 4) and age-matched Edn2+/? mice (n = 3) at the time of euthanasia 24 hours after superovulation. Note that Edn2KO ovaries and uteri were smaller than heterozygote siblings, and Edn2KO ovaries were also lighter when ovarian masses from mice aged 23–31 days were averaged (wet weight, p = 0.030). When average ovarian weight was normalized to average body weight, no significant difference remained between groups (p = 0.318).</p
Direct selection for increased litter size may put less than optimum emphasis on the components of n...
<p>Adjacent ovarian sections of the Edn2KO mice and heterozygous littermates collected at hCG24 were...
<p>(A) Representative images of agarose gels from genotypic analysis of teratomas and host somatic t...
ovaries from normal WT littermates at the same age. At the same time, no morphological features of a...
A. Body weight was decreased following the onset of CR. AL-fed POLGD257A/257A mice (D57A/D57A) denot...
The oocytes in the ovaries of virgin and multiparous mice (A, CBA, RIII and CBA \m=x\A strains) have...
<p>(A) Representative image of the reproductive tract from an <i>Rb1-cKO</i> mouse. Scale bar = 1cm....
<p>Panel A: Images of mouse peritoneal anatomy showing the abdominal fat accumulation at postnatal w...
<p>*Edn2+/? mice (5) were given no injection in this experiment and oocyte numbers are provided resp...
<p>*Edn2+/? mice were used for statistical comparison to either Edn2KO group. These Edn2KO** mice we...
<p>A total of 47 GATA6 (+/−) mice were analyzed for ovarian phenotype. The majority of mice were ana...
<p>(A) Primordial/primary oocyte numbers of <i>VC</i>; <i>Kit</i><sup><i>D818V(L)</i></sup><i>/+</i>...
<p>(A) Body weight of four core genotype (FCG) mice at day 21 and day 45, prior to gonadectomy (GDX)...
<p><b>A)</b> Representative 8 week old mice of the indicated genotype demonstrating a size differenc...
<p>(A) Genomic PCR for the βhCG transgene, using DNA derived from the peripheral blood cells of F1 m...
Direct selection for increased litter size may put less than optimum emphasis on the components of n...
<p>Adjacent ovarian sections of the Edn2KO mice and heterozygous littermates collected at hCG24 were...
<p>(A) Representative images of agarose gels from genotypic analysis of teratomas and host somatic t...
ovaries from normal WT littermates at the same age. At the same time, no morphological features of a...
A. Body weight was decreased following the onset of CR. AL-fed POLGD257A/257A mice (D57A/D57A) denot...
The oocytes in the ovaries of virgin and multiparous mice (A, CBA, RIII and CBA \m=x\A strains) have...
<p>(A) Representative image of the reproductive tract from an <i>Rb1-cKO</i> mouse. Scale bar = 1cm....
<p>Panel A: Images of mouse peritoneal anatomy showing the abdominal fat accumulation at postnatal w...
<p>*Edn2+/? mice (5) were given no injection in this experiment and oocyte numbers are provided resp...
<p>*Edn2+/? mice were used for statistical comparison to either Edn2KO group. These Edn2KO** mice we...
<p>A total of 47 GATA6 (+/−) mice were analyzed for ovarian phenotype. The majority of mice were ana...
<p>(A) Primordial/primary oocyte numbers of <i>VC</i>; <i>Kit</i><sup><i>D818V(L)</i></sup><i>/+</i>...
<p>(A) Body weight of four core genotype (FCG) mice at day 21 and day 45, prior to gonadectomy (GDX)...
<p><b>A)</b> Representative 8 week old mice of the indicated genotype demonstrating a size differenc...
<p>(A) Genomic PCR for the βhCG transgene, using DNA derived from the peripheral blood cells of F1 m...
Direct selection for increased litter size may put less than optimum emphasis on the components of n...
<p>Adjacent ovarian sections of the Edn2KO mice and heterozygous littermates collected at hCG24 were...
<p>(A) Representative images of agarose gels from genotypic analysis of teratomas and host somatic t...