<p>Fold-increases of proteins involved in NHEJ upon ORF57 expression are presented along with the number of peptide hits for each protein. UniProt numbers are shown for reference.</p
DNA double-strand breaks are the most deleterious type of DNA damage that cells experience, which ma...
<p><b>A</b> HuH7 cells were transfected with empty vector plasmid (Mock), <i>ORP8</i> cDNA (ORP8), n...
<p>(A) Schematic diagram of the Orf-I protein. The non-canonical endoplasmic reticulum (ER) retentio...
<p>(<b>A</b>) iORF57 293 cells were either uninduced, treated with 50 µM etoposide for 30 minutes to...
<p>Neutral comet assays were performed to assess double-strand breaks. (<b>A</b>) Cells were either ...
<p>(<b>A</b>) Alkaline comet assays were performed on HEK 293T cells and protein levels for each ass...
<p><i>Top</i> Nitrocellulose membrane from an ORF57 immunoprecipitation performed under HITS-CLIP co...
(A) Schematic diagram of ORF57 locus and deletion strategy. ORF56 (gray) and ORF57 (green) share a p...
(A) Representative diagrams of the constructs encoding C-terminal FLAG- or GFP-tagged ORF57 and its ...
(A) Ribo-seq reads on canonical ORF YIL060W (top) and “dubious” ORF YIL059C (bottom). The bounds of ...
Western blot analysis of ORF2 proteins containing mutations in putative phosphorylation sites. Top p...
(A, C, E & G) Representative northern blots of transcription pulse-chase assay in cells expressing a...
<p>(A) 293, 293ΔAly, 293ΔUIF and 293ΔAlyΔUIF cells were treated with 2 µg/ml doxycyclin and grown fo...
(A) The constructs of GFP-tagged ORF57, FLAG-tagged ORF57 and its truncation mutants used in the stu...
<p>(A) 293, 293ΔAly, 293ΔUIF and 293ΔAlyΔUIF cells were mock treated or treated with 2 µg/ml doxycyc...
DNA double-strand breaks are the most deleterious type of DNA damage that cells experience, which ma...
<p><b>A</b> HuH7 cells were transfected with empty vector plasmid (Mock), <i>ORP8</i> cDNA (ORP8), n...
<p>(A) Schematic diagram of the Orf-I protein. The non-canonical endoplasmic reticulum (ER) retentio...
<p>(<b>A</b>) iORF57 293 cells were either uninduced, treated with 50 µM etoposide for 30 minutes to...
<p>Neutral comet assays were performed to assess double-strand breaks. (<b>A</b>) Cells were either ...
<p>(<b>A</b>) Alkaline comet assays were performed on HEK 293T cells and protein levels for each ass...
<p><i>Top</i> Nitrocellulose membrane from an ORF57 immunoprecipitation performed under HITS-CLIP co...
(A) Schematic diagram of ORF57 locus and deletion strategy. ORF56 (gray) and ORF57 (green) share a p...
(A) Representative diagrams of the constructs encoding C-terminal FLAG- or GFP-tagged ORF57 and its ...
(A) Ribo-seq reads on canonical ORF YIL060W (top) and “dubious” ORF YIL059C (bottom). The bounds of ...
Western blot analysis of ORF2 proteins containing mutations in putative phosphorylation sites. Top p...
(A, C, E & G) Representative northern blots of transcription pulse-chase assay in cells expressing a...
<p>(A) 293, 293ΔAly, 293ΔUIF and 293ΔAlyΔUIF cells were treated with 2 µg/ml doxycyclin and grown fo...
(A) The constructs of GFP-tagged ORF57, FLAG-tagged ORF57 and its truncation mutants used in the stu...
<p>(A) 293, 293ΔAly, 293ΔUIF and 293ΔAlyΔUIF cells were mock treated or treated with 2 µg/ml doxycyc...
DNA double-strand breaks are the most deleterious type of DNA damage that cells experience, which ma...
<p><b>A</b> HuH7 cells were transfected with empty vector plasmid (Mock), <i>ORP8</i> cDNA (ORP8), n...
<p>(A) Schematic diagram of the Orf-I protein. The non-canonical endoplasmic reticulum (ER) retentio...
DOI