<div><p>Vertebrate hair cells are responsible for the high fidelity encoding of mechanical stimuli into trains of action potentials (spikes) in afferent neurons. Here, we generated a transgenic zebrafish line expressing Channelrhodopsin-2 (ChR2) under the control of the hair-cell specific <i>myo6b</i> promoter, in order to examine the role of the mechanoelectrical transduction (MET) channel in sensory encoding in afferent neurons. We performed <i>in vivo</i> recordings from afferent neurons of the zebrafish lateral line while activating hair cells with either mechanical stimuli from a waterjet or optical stimuli from flashes of ∼470-nm light. Comparison of the patterns of encoded spikes during 100-ms stimuli revealed no difference in mean f...
Complex motor behaviors are thought to be coordinated by networks of brain nuclei that may control d...
In the lateral line system, water motion is detected by neuromast organs, fundamental units that are...
Scientists have long been fascinated by how anatomical structures in the brain can generate the dive...
Vertebrate hair cells are responsible for the high fidelity encoding of mechanical stimuli into trai...
SummarySomatosensory neurons in teleosts and amphibians are sensitive to thermal, mechanical, or noc...
Somatosensory neurons in teleosts and amphibians are sensitive to thermal, mechanical, or nociceptiv...
Larval zebrafish are emerging as a model for describing the development and function of simple neura...
Hair cells transmit mechanical information by converting deflection of the hair bundle into synaptic...
Hair cells are mechanosensory receptors responsible for transducing auditory and vestibular informat...
Expression of halorhodopsin (NpHR), a light-driven microbial chloride pump, allows for optical contr...
The lateral line organ in fish and amphibians transforms fluid motion in the animal’s surroundings i...
AbstractThe molecular basis of sensory hair cell mechanotransduction is largely unknown. In order to...
In sensory hair cells of auditory and vestibular organs, the ribbon synapse is required for the prec...
Methods to label neurons and to monitor their activity with genetically encoded fluorescent reporter...
Hair cells detect and process sound and movement information, and transmit this with remarkable prec...
Complex motor behaviors are thought to be coordinated by networks of brain nuclei that may control d...
In the lateral line system, water motion is detected by neuromast organs, fundamental units that are...
Scientists have long been fascinated by how anatomical structures in the brain can generate the dive...
Vertebrate hair cells are responsible for the high fidelity encoding of mechanical stimuli into trai...
SummarySomatosensory neurons in teleosts and amphibians are sensitive to thermal, mechanical, or noc...
Somatosensory neurons in teleosts and amphibians are sensitive to thermal, mechanical, or nociceptiv...
Larval zebrafish are emerging as a model for describing the development and function of simple neura...
Hair cells transmit mechanical information by converting deflection of the hair bundle into synaptic...
Hair cells are mechanosensory receptors responsible for transducing auditory and vestibular informat...
Expression of halorhodopsin (NpHR), a light-driven microbial chloride pump, allows for optical contr...
The lateral line organ in fish and amphibians transforms fluid motion in the animal’s surroundings i...
AbstractThe molecular basis of sensory hair cell mechanotransduction is largely unknown. In order to...
In sensory hair cells of auditory and vestibular organs, the ribbon synapse is required for the prec...
Methods to label neurons and to monitor their activity with genetically encoded fluorescent reporter...
Hair cells detect and process sound and movement information, and transmit this with remarkable prec...
Complex motor behaviors are thought to be coordinated by networks of brain nuclei that may control d...
In the lateral line system, water motion is detected by neuromast organs, fundamental units that are...
Scientists have long been fascinated by how anatomical structures in the brain can generate the dive...