Bcl-2 and Bax expression in kidney tissue 24 h after reperfusion.

<p>(<b>A</b>) almost absence of Bcl-2 expression on proximal tubules of sham operated animals (<b>B</b>) Bax protein in the sham-operated animals exclusively on distal tubule (<b>C</b>) up-regulated Bcl-2 expression on tubular cells in ARF animals (<b>D</b>) widely and strong expression of Bax expended on proximal tubular cells in ARF animals (<b>E</b>) slight expression of Bcl-2 protein in group treated with losartan (<b>F</b>) reduced Bax protein expression after ischemic-reperfusion injury in losartan treated rats.