<p>Immunofluorescence staining of heart allograft sections stained with Abs to CD68 (FITC, green) and IP-10 (TMRITC, red). Nuclei were counterstained with DAPI (blue). The IP-10 expression in CD68 positive infiltrating monocytes was reduced after PrA treatment. The results are representative of three independent experiments (n = 3).</p
Background: Chronic rejection can prevent long-term survival of organ transplants. Although the bene...
<p>Infiltration of CD11b-positive cells by epicardial transplantation (panel A) was similar to that ...
CXCL10–CXCR3 axis plays a pivotal role in cardiac allograft rejection, so that targeting CXCL10 with...
<p>(A) The heart allograft was harvested on day seven post heart transplantation, sectioned, and sta...
<p>(A) The effect of PrA administration on IP-10 mRNA expression in heart allografts of recipient ra...
The immunosuppressant Protosappanin A (PrA), isolated from the medicinal herb, promotes cardiac allo...
<p>IP-10 (50 ng/ml), Mig (100 ng/ml), or SDF-1 (100 ng/ml) was added to the PBMC supernatant. T cell...
<p>(A) SD rats were transplanted with Wistar cardiac allograft and received different treatment post...
<p>Both PrA and PrA-treated DC infusion suppressed IL-12p70 production (A) and enhanced IL-10 produc...
<p>The naïve T cells isolated from rat spleen were cultured with or without PrA (20 nM) for 72 h. A ...
<p>(A and B) Distribution of CD45<sup>+</sup> leukocytes in cardiac allografts treated with anti-MCP...
<p>Control and PrA-treated PBMCs from recipient rats (n = 8) were separately isolated on day seven p...
<p>PBMC and spleen T cells were isolated from recipient control and PrA-treated rats on day seven po...
<p>DCs (Wistar) were treated with LPS alone or LPS plus PrA (5, 20, or 40 nM) from days 7 to 9 in vi...
<p>DCs were treated with LPS alone or LPS plus PrA (5 or 20 nM) from days 7 to 9 in vitro. The cytok...
Background: Chronic rejection can prevent long-term survival of organ transplants. Although the bene...
<p>Infiltration of CD11b-positive cells by epicardial transplantation (panel A) was similar to that ...
CXCL10–CXCR3 axis plays a pivotal role in cardiac allograft rejection, so that targeting CXCL10 with...
<p>(A) The heart allograft was harvested on day seven post heart transplantation, sectioned, and sta...
<p>(A) The effect of PrA administration on IP-10 mRNA expression in heart allografts of recipient ra...
The immunosuppressant Protosappanin A (PrA), isolated from the medicinal herb, promotes cardiac allo...
<p>IP-10 (50 ng/ml), Mig (100 ng/ml), or SDF-1 (100 ng/ml) was added to the PBMC supernatant. T cell...
<p>(A) SD rats were transplanted with Wistar cardiac allograft and received different treatment post...
<p>Both PrA and PrA-treated DC infusion suppressed IL-12p70 production (A) and enhanced IL-10 produc...
<p>The naïve T cells isolated from rat spleen were cultured with or without PrA (20 nM) for 72 h. A ...
<p>(A and B) Distribution of CD45<sup>+</sup> leukocytes in cardiac allografts treated with anti-MCP...
<p>Control and PrA-treated PBMCs from recipient rats (n = 8) were separately isolated on day seven p...
<p>PBMC and spleen T cells were isolated from recipient control and PrA-treated rats on day seven po...
<p>DCs (Wistar) were treated with LPS alone or LPS plus PrA (5, 20, or 40 nM) from days 7 to 9 in vi...
<p>DCs were treated with LPS alone or LPS plus PrA (5 or 20 nM) from days 7 to 9 in vitro. The cytok...
Background: Chronic rejection can prevent long-term survival of organ transplants. Although the bene...
<p>Infiltration of CD11b-positive cells by epicardial transplantation (panel A) was similar to that ...
CXCL10–CXCR3 axis plays a pivotal role in cardiac allograft rejection, so that targeting CXCL10 with...