Immunohistochemical Scoring of Notch Signaling Components in the whole cohort of pediatric patients with rhabdomyosarcomas (RMS) and in alveolar (PAX3-FOXO1, n = 10; PAX7-FOXO1, n = 2) and embryonal (n = 20) RMS subtypes.
- Maria De Salvo (559745)
- Lavinia Raimondi (559746)
- Serena Vella (559747)
- Laura Adesso (559748)
- Roberta Ciarapica (559749)
- Federica Verginelli (559750)
- Antonio Pannuti (444963)
- Arianna Citti (130369)
- Renata Boldrini (47443)
- Giuseppe M. Milano (559751)
- Antonella Cacchione (559752)
- Andrea Ferrari (305970)
- Paola Collini (305972)
- Angelo Rosolen (84555)
- Gianni Bisogno (285565)
- Rita Alaggio (305975)
- Alessandro Inserra (559753)
- Mattia Locatelli (559754)
- Stefano Stifani (183044)
- Isabella Screpanti (120411)
- Lucio Miele (81383)
- Franco Locatelli (130400)
- Rossella Rota (559755)
Publication date
May 2014
DOIAbstract
<p>Data are expressed as median values semi-quantified as the percentage of positive nuclei per microscopic field (range in parentheses). Alveolar tumors were confirmed as PAX-FOXO1 fusion positive and Embryonal tumors as PAX-FOXO1 fusion-negative).</p><p>*<i>P</i>: Mann-Whitney test for ARMS <i>vs</i> ERMS values;</p>†<p><i>P</i> and ‡<i>P</i>: Fisher's exact test for Notch3 <i>vs</i> Notch1 and HES1 <i>vs</i> HEY1 values within each RMS subtype, respectively.</p
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