The overall FC-SC relationships.

<p>(A) The probability densities of FC strengths between structurally connected and unconnected regions pairs. When direct SC presents, higher FC strength appears than the case direct SC absents, indicating a robust relationship between FC and SC. (B) Scatter plot of SC strength against FC strength for the regions with direct SC. Further analysis showed significant coefficient between FC and SC strengths for all groups. Data are from group averaged functional connectivity matrix of AD, aMCI, and NC groups, at the high resolution (1024×1024).