<p>: A) Body mass, B) Forelimb and hind limb grip strength, C) Grid-hang time, and D) Rotarod performance over 10 to 18 weeks of age. Tests were performed on a weekly basis. Data from mice under assessment with either vehicle or <i>tirasemtiv</i> were excluded from these figures for that week. Data are expressed as mean ± SEM. n = 24/group.</p
© 2015 John Wiley & Sons A/S. This study compared the capacity of young and old male C57Bl/6J mice t...
<p>At week 10, all groups of R6/2 mice displayed significantly lower weights compared to their WT co...
<p>Performance values of (A) Forelimb grip strength, (B) Hindlimb grip strength, (C) Hang test perfo...
<p>Both male (A) and female (B) <i>Hdh</i>Q150 mice performed better on the rotarod compared to cont...
<p>(A-B) Grip strength as latency to fall (sec) and body weights (g) in Ntg and SOD1<sup>G93A</sup> ...
<p>(A) Decline of physical performance by Rotarod analysis in knock-in mice. (B) Progressive impairm...
<p>(A) Weight measurements of WT and VCP<sup>R155H/+</sup> mice. (B) Muscle strength impairment obse...
(A&B) Quantification of RotaRod studies. (A) Female Gnao1+/G184S mice lose the ability to stay on a ...
<p>* R6/1 mice significantly different from age-matched WT littermates at <i>p</i><.05, ** at <i>p</...
<p>(<b>A</b>) Latency to fall from the rotarod. (<b>B</b>) Bodyweight measurements from 4 to 10 week...
<p>(A) IMM was evaluated in Ntg and longitudinally in SOD1<sup>G93A</sup> mice at 12, 14, 17 and 20 ...
<p>(A) Body weight and (B) grip strength. Data are expressed as the mean ± SEM of the following numb...
<p>(A) Experimental protocol. Mice were scanned for MRI measures at 4, 8, 12 and 14 weeks of age. Th...
<p>(A to C) Age-matched (4 and 7 month) male mice (n = 13 for WT and 12 for rpS6<sup>P−/−</sup> mice...
<p>(A) Incidence and latency of lordokyphosis. A log rank test was used for statistical analysis: <i...
© 2015 John Wiley & Sons A/S. This study compared the capacity of young and old male C57Bl/6J mice t...
<p>At week 10, all groups of R6/2 mice displayed significantly lower weights compared to their WT co...
<p>Performance values of (A) Forelimb grip strength, (B) Hindlimb grip strength, (C) Hang test perfo...
<p>Both male (A) and female (B) <i>Hdh</i>Q150 mice performed better on the rotarod compared to cont...
<p>(A-B) Grip strength as latency to fall (sec) and body weights (g) in Ntg and SOD1<sup>G93A</sup> ...
<p>(A) Decline of physical performance by Rotarod analysis in knock-in mice. (B) Progressive impairm...
<p>(A) Weight measurements of WT and VCP<sup>R155H/+</sup> mice. (B) Muscle strength impairment obse...
(A&B) Quantification of RotaRod studies. (A) Female Gnao1+/G184S mice lose the ability to stay on a ...
<p>* R6/1 mice significantly different from age-matched WT littermates at <i>p</i><.05, ** at <i>p</...
<p>(<b>A</b>) Latency to fall from the rotarod. (<b>B</b>) Bodyweight measurements from 4 to 10 week...
<p>(A) IMM was evaluated in Ntg and longitudinally in SOD1<sup>G93A</sup> mice at 12, 14, 17 and 20 ...
<p>(A) Body weight and (B) grip strength. Data are expressed as the mean ± SEM of the following numb...
<p>(A) Experimental protocol. Mice were scanned for MRI measures at 4, 8, 12 and 14 weeks of age. Th...
<p>(A to C) Age-matched (4 and 7 month) male mice (n = 13 for WT and 12 for rpS6<sup>P−/−</sup> mice...
<p>(A) Incidence and latency of lordokyphosis. A log rank test was used for statistical analysis: <i...
© 2015 John Wiley & Sons A/S. This study compared the capacity of young and old male C57Bl/6J mice t...
<p>At week 10, all groups of R6/2 mice displayed significantly lower weights compared to their WT co...
<p>Performance values of (A) Forelimb grip strength, (B) Hindlimb grip strength, (C) Hang test perfo...