Feedback

Blocking aSyn phosphorylation reduces membrane interactions and accelerates inclusion formation.

  • Sandra Tenreiro (13787)
  • Madalena M. Reimão-Pinto (561214)
  • Pedro Antas (561215)
  • José Rino (81063)
  • Donata Wawrzycka (561216)
  • Diana Macedo (561217)
  • Rita Rosado-Ramos (561218)
  • Triana Amen (561219)
  • Meytal Waiss (561220)
  • Filipa Magalhães (561221)
  • Andreia Gomes (561222)
  • Cláudia N. Santos (561223)
  • Daniel Kaganovich (561224)
  • Tiago Fleming Outeiro (199633)
Open link
Publication date
May 2014
Icon DOI
10.1371/journal.pgen.1004302.g007

Abstract

<p>(A) Time lapse confocal imaging comparing the distribution of WT or S129A aSyn-GFP at the indicated time points after induction of aSyn expression. Nuclei were visualized by co-expressing NLS-TagRFP657. (B) Percentage of WT and S129A aSyn-GFP expressing cells presenting inclusions over time. n<sub>wt</sub> = 48 cells, n<sub>S129A</sub> = 55 cells. Inclusions were recognized by measuring GFP intensity.</p

Extracted data

We use cookies to provide a better user experience.
Data Protection