<p>The table compares to wild type (+/+), at different ages of developing mutant mouse long bones, the whole growth plate (GP), hypertrophic (HZ) and proliferating zone (PZ) thickness, cortical bone thickness, trabecular bone volume (BV/TV), osteoclast surface/number and osteoid thickness.</p
<p>(A) Von Kossa/van Gieson staining of non-decalcified vertebral body sections from 24 weeks old fe...
<p>(A) Staining of newborn skeletons with Alizarin red (bone) and Alcian blue (cartilage) reveals un...
<p>(A) Structural parameters of wild-type (+/+) and homozygous (−/−) femora at 8 weeks of age charac...
International audienceAdult Ibsp-knockout mice (BSP2/2) display shorter stature, lower bone turnover...
<p>(A) Xray analysis demonstrates absence of gross skeletal abnormalities in 6 weeks old <i>Thbs4</i...
<p>(A) Von Kossa/van Gieson staining of spine sections from 6 and 26 weeks old wildtype (+/+) and <i...
<p>(A) Toluidine blue staining of non-decalcified vertebral body sections from 6 weeks old female wi...
Bone morphogenetic proteins (BMPs) have a major role in tissue development. BMP3 is synthesized in o...
<p>(A): Alcian Blue/Alizarin Red S staining at different developmental (E14.5, E18.5) and postnatal ...
<p>(A) Fluorescent images of proximal tibias, distal femurs, distal metacarpals, and proximal foreli...
<p>(A) 3D µCT reconstruction and morphometry of newborn whole femurs from BSP+/+ (+/+) and −/− newbo...
<p>(A) μCT 3-D reconstruction of metaphyseal trabecular bone of the femur from WT, HeyL<sup>−/−</sup...
<p>Data are Mean±SEM of N = 7 to 8 newborn and 4 to 6 adult mice; *:p<0.05, **:p<0.001 vs BSP+/+ Man...
<p>Histomorphometric analysis of distal femoral metaphysis in male mice showing (a) cancellous bone ...
International audienceBone sialoprotein regulates osteoblast activity and bone formation. In knockou...
<p>(A) Von Kossa/van Gieson staining of non-decalcified vertebral body sections from 24 weeks old fe...
<p>(A) Staining of newborn skeletons with Alizarin red (bone) and Alcian blue (cartilage) reveals un...
<p>(A) Structural parameters of wild-type (+/+) and homozygous (−/−) femora at 8 weeks of age charac...
International audienceAdult Ibsp-knockout mice (BSP2/2) display shorter stature, lower bone turnover...
<p>(A) Xray analysis demonstrates absence of gross skeletal abnormalities in 6 weeks old <i>Thbs4</i...
<p>(A) Von Kossa/van Gieson staining of spine sections from 6 and 26 weeks old wildtype (+/+) and <i...
<p>(A) Toluidine blue staining of non-decalcified vertebral body sections from 6 weeks old female wi...
Bone morphogenetic proteins (BMPs) have a major role in tissue development. BMP3 is synthesized in o...
<p>(A): Alcian Blue/Alizarin Red S staining at different developmental (E14.5, E18.5) and postnatal ...
<p>(A) Fluorescent images of proximal tibias, distal femurs, distal metacarpals, and proximal foreli...
<p>(A) 3D µCT reconstruction and morphometry of newborn whole femurs from BSP+/+ (+/+) and −/− newbo...
<p>(A) μCT 3-D reconstruction of metaphyseal trabecular bone of the femur from WT, HeyL<sup>−/−</sup...
<p>Data are Mean±SEM of N = 7 to 8 newborn and 4 to 6 adult mice; *:p<0.05, **:p<0.001 vs BSP+/+ Man...
<p>Histomorphometric analysis of distal femoral metaphysis in male mice showing (a) cancellous bone ...
International audienceBone sialoprotein regulates osteoblast activity and bone formation. In knockou...
<p>(A) Von Kossa/van Gieson staining of non-decalcified vertebral body sections from 24 weeks old fe...
<p>(A) Staining of newborn skeletons with Alizarin red (bone) and Alcian blue (cartilage) reveals un...
<p>(A) Structural parameters of wild-type (+/+) and homozygous (−/−) femora at 8 weeks of age charac...