Intestinal inflammation in BB rats.

<p>Representative images of the myenteric ganglia and the muscular layer of the jejunum as stained by H&E (A). Intra-ganglionic infiltration of PMN cells (arrows) and thicker muscular layers were observed in both inflamed and diabetic rats. All scale bars: 50 µm. Numbers of PMN cells per 50 myenteric ganglia (B) in both inflamed and diabetic rats increased, compared to control rats (**<i>p</i><0.01, *<i>p</i><0.05, respectively). Sum of circular and longitudinal muscular layer thickness (C) in both inflamed and diabetic rats increased, compared to control rats (**<i>p</i><0.01, ***<i>p</i><0.001, respectively by One-way ANOVA followed by Dunnett <i>post hoc</i> test). Jejunal MPO activity (D) in both inflamed rats and diabetic rats increased, compared to control rats (**<i>p</i><0.01, *<i>p</i><0.05,). Jejunal iNOS mRNA expression (E) in both inflamed and diabetic rats increased, compared to control rats (**<i>p</i><0.01). If not mentioned, <i>p</i> values were obtained by Kruskal-Wallis test followed by Steel <i>post hoc</i> test.