Phylogeny of the 11 genomic segments of the CAU12-2-51 strain.

<p>The different genotypes within each segment are indicated. Numbers at the nodes indicate the level of bootstrap support (%) based on neighbor-joining analysis of 1000 resampled datasets. Only values above 70% are provided. The CAU12-2-51 strain is marked in bold type and indicated by filled circles. Color coded boxes are used to differentiate strains of origin: human (light blue), bovine (green), feline (red), human/bovine-like (yellow), human/feline-like (purple), feline/bovine-like (blue), canine/bovine-like (orange), guanaco/feline-like (dark blue), and antelope/bovine-like (light green). Genotype origins are designated as follows: G, glycosylated; P, protease sensitive; I, intermediate capsid shell; R, RNA-dependent RNA polymerase; C, core shell protein; M, methyltransferase; A, interferon antagonist; N, NTPase; T, translation enhancer; E, enterotoxin; H, phosphoprotein.