Relaxant reactivity after short and long-term recovery following Sham or CPB.

<p><i>Left panels</i>: relaxant reactivity of mesenteric arteries to ACh. <b>A</b>: concentration-response curves for Sham groups, % of relaxation; <b>B</b>: concentration-response curves for CPB groups, % of relaxation; <b>C</b>: AUC values of the relaxant responses to ACh, au. <i>Right panels</i>: relaxant reactivity of coronary arteries to ACh. <b>D</b>: concentration-response curves for Sham groups, % of relaxation; <b>E</b>: concentration-response curves for CPB groups, % of relaxation; <b>F</b>: AUC values of the relaxant responses to ACh, au. Abbreviations: CBP, cardiopulmonary bypass; PE, phenylephrine; SE, serotonin. Data are mean±SEM. <b>a</b>- indicates P<0.05 vs Control-Vehicle, t-test. <b>b</b>- indicates P<0.05 vs Sham 2 days, t-test.