Wild type, Q38A, and Y52E damaged error rates.

<p>Data from the lesion bypass fidelity assay as described in Materials and Methods. Error rates were calculated from sequencing between 23 and 47 dark blue plaques per experiment, with each plaque representing a unique bypass event. Substrate to polymerase ratios were 1∶1. White bars indicate the absence of RPA. Dark Grey bars indicate the addition of 5 fold RPA over substrate. <b>A.</b> 8-oxoG to T error rates (10⁻⁴) (misincorporation of dATP opposite 8-oxoG) when copying 75mer templates. <b>B.</b> 3′-T to A and <b>C.</b> 3′-T to C error rates (10⁻⁴) (misincorporation of dGTP and dTTP, respectively) when copying 75mer templates containing T-T CPD.