<p>Filled symbols for males (squares) and females (circles) represent affected individuals, and empty, unaffected ones. An arrow denotes the proband. A symbol with dot indicates the individual younger than the average age of onset, who is mutation carrier but does not present hearing loss (a mutation carrier). Symbols with asterisk are individuals who have had clinical and genetic tests.</p
<p>The solid squares (male) and circles (female) represent affected patients. The proband of each fa...
<p>Filled symbols indicate family members with either <i>systemic mastocytosis</i> (<i>SM</i>), acco...
<p>Filled squares and circles represent the male and female patients, respectively. Closed squares a...
<p>Filled symbols for males (squares) and females (circles) represent affected individuals, and empt...
<p>Genetic analyses were performed on all individuals indicated by filled, divided and open symbols....
<p>Unfilled circles indicate unaffected females, unfilled squares indicate unaffected males, filled ...
<p>Circles and squares represent females and males, respectively. Clear symbols represent unaffected...
<p>Filled symbol indicates the proband (II-2). Shaded symbols indicate asymptomatic individuals carr...
<p>(A): Pedigree of family LD-101 with hearing loss. This pedigree demonstrates nonsyndromic hearing...
<p>The family history reveals 22 affected members in 4 generations. The dark symbols represent the a...
<p>A) Pedigree for a family with the <i>PSEN1 A79V</i> mutation. B) Pedigree for a family with the <...
<p>The proband is marked with an arrow. Black symbols indicate clinically affected family members, o...
<p>Squares and circles denote males and females, respectively. Filled symbols indicate deaf individu...
<p>Hearing-impaired individuals are indicated by filled symbols. Arrows denote probands. Subjects us...
<p>Black symbols indicate clinically affected family members, open symbols indicate unaffected, and ...
<p>The solid squares (male) and circles (female) represent affected patients. The proband of each fa...
<p>Filled symbols indicate family members with either <i>systemic mastocytosis</i> (<i>SM</i>), acco...
<p>Filled squares and circles represent the male and female patients, respectively. Closed squares a...
<p>Filled symbols for males (squares) and females (circles) represent affected individuals, and empt...
<p>Genetic analyses were performed on all individuals indicated by filled, divided and open symbols....
<p>Unfilled circles indicate unaffected females, unfilled squares indicate unaffected males, filled ...
<p>Circles and squares represent females and males, respectively. Clear symbols represent unaffected...
<p>Filled symbol indicates the proband (II-2). Shaded symbols indicate asymptomatic individuals carr...
<p>(A): Pedigree of family LD-101 with hearing loss. This pedigree demonstrates nonsyndromic hearing...
<p>The family history reveals 22 affected members in 4 generations. The dark symbols represent the a...
<p>A) Pedigree for a family with the <i>PSEN1 A79V</i> mutation. B) Pedigree for a family with the <...
<p>The proband is marked with an arrow. Black symbols indicate clinically affected family members, o...
<p>Squares and circles denote males and females, respectively. Filled symbols indicate deaf individu...
<p>Hearing-impaired individuals are indicated by filled symbols. Arrows denote probands. Subjects us...
<p>Black symbols indicate clinically affected family members, open symbols indicate unaffected, and ...
<p>The solid squares (male) and circles (female) represent affected patients. The proband of each fa...
<p>Filled symbols indicate family members with either <i>systemic mastocytosis</i> (<i>SM</i>), acco...
<p>Filled squares and circles represent the male and female patients, respectively. Closed squares a...