<p>MT-4 cells (A) and CD4+ T lymphocytes (B) were stimulated with ISDs (ING-A, ING-B, ING-C), bryostatin (bryo), prostratin (prost) and PMA for 48 h. Surface marker expression was evaluated by cytometry. CD4+ T cells were also evaluated for the activation markers CD25, CD38, HLA-DR (C) and CD69 (D). Results are representative of the mean and standard deviation of three independent experiments. DMSO 1% was used as vehicle control.</p
<p>(A) The frequency of CD4<sup>+</sup>CD44<sup>+</sup>CD69<sup>+</sup> T cells from normal controls...
<p>Blood-derived PBMCs from three healthy donors were transfected with pLTR-luc and then treated wit...
<p>Purified CD4<sup>+</sup> T cells from healthy controls were cultured for 5h with PMA, ionomycin a...
<p>(<b>A</b>) Jurkat cells were treated either with bryostatin (25 nM) or left untreated for 0 to 48...
<p>MT-4 cells (A) and human CD4+ T lymphocytes (B) were treated with 0.1 µM of each PKC inhibitor (G...
<p><i>A</i>, Intracellular cytokine staining on splenocytes differentiated under T<sub>H</sub>1, T<s...
<p>Blood from 4 uninfected donors was split and one half was used to purify resting CD4<sup>+</sup> ...
<p>SMARTA or 2D2 splenocytes were stimulated with 10 µM antigen for various time points and CD69 (A)...
<p>(<b>A</b>) Frequencies of CD4<sup>+</sup> cells in draining LN that are CD69<sup>+</sup> on day 9...
<p>Expression of cell surface markers (MHCII, CD40, CD80, and CD86) on mouse BMDCs pulsed with ES pr...
<p>A and B illustrate the expression surface markers hCD4 and HLA DR/DQ on PBMCs, respectively. C di...
CD14+ monocytes were cultured with 100 ng/ml IL-4, 80 ng/ml GM-CSF ± MDA-MB231-, HeLa-, HT29-, WM278...
<p>ICOS<sup>+/+</sup> (black lines) and ICOS<sup>+/−</sup> (grey line) T cells were isolated and sti...
<p>A. Purified PBLs were stimulated for 12 days with CD3/CD28 beads, after which cells were stimulat...
<p>CFSE labeled splenocytes differentiated under T<sub>H</sub>1, T<sub>H</sub>2, T<sub>H</sub>17, or...
<p>(A) The frequency of CD4<sup>+</sup>CD44<sup>+</sup>CD69<sup>+</sup> T cells from normal controls...
<p>Blood-derived PBMCs from three healthy donors were transfected with pLTR-luc and then treated wit...
<p>Purified CD4<sup>+</sup> T cells from healthy controls were cultured for 5h with PMA, ionomycin a...
<p>(<b>A</b>) Jurkat cells were treated either with bryostatin (25 nM) or left untreated for 0 to 48...
<p>MT-4 cells (A) and human CD4+ T lymphocytes (B) were treated with 0.1 µM of each PKC inhibitor (G...
<p><i>A</i>, Intracellular cytokine staining on splenocytes differentiated under T<sub>H</sub>1, T<s...
<p>Blood from 4 uninfected donors was split and one half was used to purify resting CD4<sup>+</sup> ...
<p>SMARTA or 2D2 splenocytes were stimulated with 10 µM antigen for various time points and CD69 (A)...
<p>(<b>A</b>) Frequencies of CD4<sup>+</sup> cells in draining LN that are CD69<sup>+</sup> on day 9...
<p>Expression of cell surface markers (MHCII, CD40, CD80, and CD86) on mouse BMDCs pulsed with ES pr...
<p>A and B illustrate the expression surface markers hCD4 and HLA DR/DQ on PBMCs, respectively. C di...
CD14+ monocytes were cultured with 100 ng/ml IL-4, 80 ng/ml GM-CSF ± MDA-MB231-, HeLa-, HT29-, WM278...
<p>ICOS<sup>+/+</sup> (black lines) and ICOS<sup>+/−</sup> (grey line) T cells were isolated and sti...
<p>A. Purified PBLs were stimulated for 12 days with CD3/CD28 beads, after which cells were stimulat...
<p>CFSE labeled splenocytes differentiated under T<sub>H</sub>1, T<sub>H</sub>2, T<sub>H</sub>17, or...
<p>(A) The frequency of CD4<sup>+</sup>CD44<sup>+</sup>CD69<sup>+</sup> T cells from normal controls...
<p>Blood-derived PBMCs from three healthy donors were transfected with pLTR-luc and then treated wit...
<p>Purified CD4<sup>+</sup> T cells from healthy controls were cultured for 5h with PMA, ionomycin a...