Microcephalin expression in EOC validation set samples correlates with tumour grade.

<p>Ai. Normal ovarian epithelial tissue with high Microcephalin expression. Aii-iv. Adenocarcinoma TMA cores showing strong Microcephalin expression in a low grade tumour (Aii), moderate Microcephalin in grade 2 (Aiii) and low levels of nuclear Microcephalin expression in a high grade tumour (Aiv). All images are 40x magnification. B. The correlation between nuclear Microcephalin expression decreases with increasing tumor grade (<i>p</i><0.0001 using an ANOVA test).