RNA library for SELEX and RNA aptamer sequences.

<p>(A) The sequence of the RNA pool for <i>in vitro</i> selection is shown. The random RNA library was produced by PCR and <i>in vitro</i> transcription of DNA template containing 40 random sequences. (B) The RNAs selected after the 12th round of SELEX were sequenced and grouped based on sequence similarity. Four groups of RNA aptamers were obtained (frequency is depicted in parentheses) and representative RNA sequences of each group are shown (the conserved sequences of each group are underlined).