A convenient and efficient one-pot method for the synthesis of novel acridine-calix[4]arene derivatives as new DNA binding agents via multicomponent reaction

<div><p>A new approach is applied for the synthesis of novel acridine-calix[4]arene derivatives via a multicomponent reaction. These compounds have been characterised by ¹H NMR, ¹³C NMR and HR-MS. Our binding studies between acridine-functionalised calix[4]arenes and calf thymus DNA (CT-DNA) via fluorescence titration show that these compounds have a good affinity to CT-DNA.</p>