<p>(<b>A</b>) Time scheme of the LEL model. Arrows indicate time points of tissue collection. Tissue samples were collected prior to culturing (TM t = 0 h), after washing (TM t = 2 h), as well during and after completion of epithelial cell release by EDTA treatment (LEL-M t = 3/4/5 h). As a control, tissue samples were collected from TM cultured for 5 h (TM t = 5 h). (<b>B</b>) LEL induces gene expression of <i>IL1B</i>, <i>IL6</i>, <i>IL8</i>, <i>IL23A</i>, <i>TNFA, IFNG</i>, and <i>CCL2</i> in resident lamina propria cells. Transcript levels of cytokines/chemokines were determined by qRT-PCR in tissue samples collected as described in (A). Shown are the mean normalized transcript numbers ± SEM of at least 4 independent experiments. Gray b...
<p>LECs were grown on Matrigel in the presence or absence of IL-8, IL-6 or VEGF-A and lymphatic netw...
<p>hPdLC were stimulated with <i>P. gingivalis</i> LPS in the presence or in the absence of AEA for ...
<p>(A) RNA markers of stem cells (<i>Lgr5</i>), enterocytes (<i>Alpi</i>), and goblet cells (<i>Muc2...
<p>(<b>A</b>) LEL induces gene expression of <i>CD14</i>, <i>CD86</i>, <i>TLR2</i>, and <i>CD54</i> ...
<p>Frozen tissue samples collected prior to culturing (TM 0 h) and immediately after release of the ...
<div><p>Resident human lamina propria immune cells serve as powerful effectors in host defense. Mole...
<p>(<b>A</b>) The overlap of differentially expressed genes in the LEL model <i>in vitro</i> and in ...
Despite the close proximity of intestinal resident lamina propria (LP) cells to bacterial and dietar...
<p>(A,B) Beas-2B cells were infected with the <i>B. anthracis</i> strains RP9 and RPLC2 at an MOI of...
<p>Microarray map AAH-CYT-6 was used to assess chemokine/cytokine expression in the cell-free supern...
<p>(<b>A</b>-<b>C</b>) Single cell suspension was isolated from non-treated wild type mice, 3, or 7 ...
Lymphatic endothelial cells (LECs) line the lymphatic vessels and lymph node sinuses. They function...
<p>(A) Mean relative gene expression levels are presented in MDM and AM before and after 4–24 hour L...
<p>EPL cells were dissociated and reaggregated in unsupplemented tissue culture medium (○) or medium...
Three-color immunofluorescence and flow cytometric analysis showed that the vast majority of normal ...
<p>LECs were grown on Matrigel in the presence or absence of IL-8, IL-6 or VEGF-A and lymphatic netw...
<p>hPdLC were stimulated with <i>P. gingivalis</i> LPS in the presence or in the absence of AEA for ...
<p>(A) RNA markers of stem cells (<i>Lgr5</i>), enterocytes (<i>Alpi</i>), and goblet cells (<i>Muc2...
<p>(<b>A</b>) LEL induces gene expression of <i>CD14</i>, <i>CD86</i>, <i>TLR2</i>, and <i>CD54</i> ...
<p>Frozen tissue samples collected prior to culturing (TM 0 h) and immediately after release of the ...
<div><p>Resident human lamina propria immune cells serve as powerful effectors in host defense. Mole...
<p>(<b>A</b>) The overlap of differentially expressed genes in the LEL model <i>in vitro</i> and in ...
Despite the close proximity of intestinal resident lamina propria (LP) cells to bacterial and dietar...
<p>(A,B) Beas-2B cells were infected with the <i>B. anthracis</i> strains RP9 and RPLC2 at an MOI of...
<p>Microarray map AAH-CYT-6 was used to assess chemokine/cytokine expression in the cell-free supern...
<p>(<b>A</b>-<b>C</b>) Single cell suspension was isolated from non-treated wild type mice, 3, or 7 ...
Lymphatic endothelial cells (LECs) line the lymphatic vessels and lymph node sinuses. They function...
<p>(A) Mean relative gene expression levels are presented in MDM and AM before and after 4–24 hour L...
<p>EPL cells were dissociated and reaggregated in unsupplemented tissue culture medium (○) or medium...
Three-color immunofluorescence and flow cytometric analysis showed that the vast majority of normal ...
<p>LECs were grown on Matrigel in the presence or absence of IL-8, IL-6 or VEGF-A and lymphatic netw...
<p>hPdLC were stimulated with <i>P. gingivalis</i> LPS in the presence or in the absence of AEA for ...
<p>(A) RNA markers of stem cells (<i>Lgr5</i>), enterocytes (<i>Alpi</i>), and goblet cells (<i>Muc2...