Atherosclerotic plaque level in apoE^−/− mice fed a high-fat diet (control) or a diet with 5% SPH.

<p>After 12 weeks of dietary treatment, whole aorta was collected and <i>en-face</i> analysis was performed to quantify aortic surface covered by atherosclerotic plaques. Bars represent means ± SD of 12 mice for each diet. Unpaired <i>t</i>-test was used to detect statistical significance (*P<0.05).