Transcript and protein expression levels of IGF-II receptor (A, B), IGF-II (C, E) and APP (D, F) in MS and MS9II cells.

<p>Increased levels and expression of IGF-II receptor in MS9II <i>vs</i> MS cells are validated using Western blotting and immunofluorescence staining respectively (A, B). Histograms showing decreased level of <i>Igf2</i> mRNA (C) and increased level of <i>App</i> mRNA in MS9II cells compared to MS cells as obtained using AD-PCR-Array. Immunoblots and respective histograms validating decreased levels of IGF-II and increased levels of APP in MS9II cells. The protein levels were normalized to the β-actin and the values from four different experiment are expressed as means ± SEM, **<i>p</i><0.01. Scale bar = 10 µm.