Expression of Mitf, GATA1 and c/EBPα correlated to the expression levels of miRNAs that potentially target these transcripts.

<p>(A). Expression levels of Mitf, GATA1 and c/EBPα were determined by qPCR. (B) Potential miRNAs targeting the 3′-UTR of Mitf, GATA1 and c/EBPα were identified by TargetScan and Miranda database and IPA ingenuity system. Blue represents decreased expression of miRNAs, whereas yellow is for increased expressed miRNAs. (C). The fold changes of potential regulating miRNAs were calculated based on the fluorescence index of each miRNA at different time-points, after normalization to that of the respective miRNAs in the control group (isolated bone marrow cells). Values are presented as mean ±SEM (n = 4∼6), **P<0.001 (vs. BM). *P<0.01 (vs. BM).