Oxidative damage biomarkers in heart (mean ± SD): lipoperoxides (LPO), total glutathione (TG) reduced glutathione (GSH), catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GRd) and glutathione transferase (GST) for each group (N = 36; 6 animals/group).

<p>Control (12h light/12h darkness; L:D); exposure to permanent illumination (24h L); exposure to darkness (22h D) with light sessions between 4 and 6 p.m. ; injected with Adriamycin (AD) (12h/12h L:D); AD + L; AD + D. P<0.05 minimum significance level.</p><p><i>^ap<0,001</i> vs control; <i>^bp<0,01</i> vs control.</p><p>^<i>d</i>p<0,001 L vs D.</p><p><i>^gp<0,001</i> AD+L or AD+D vs AD; <i>ⁱp<0,05</i> AD+L or AD+D vs AD.</p><p><i>^jp<0,001</i> AD+L vs AD+D; <i>^kp<0,01</i> AD+L vs AD+D; <i>^lp<0,05</i> AD+L vs AD+D.