Geographical distribution of antibody responses to lineage-specific synthetic peptides, as determined by ELISA.

<p>EHC = Endemic healthy controls (* a further 17 Colombian sera that were serologically negative with the lysate were included in the peptide ELISAs as additional controls); ND = not determined.</p>a<p>these 98 comprised 1 sample from each of 90 patients, plus 2 paired samples from each of 4 patients. All eight paired samples reacted with TSSApep-II/V/VI, and are included within the 67 Brazilian reactors to this peptide. 1 set of these pairs also reacted with TSSApep-V/VI.</p>b<p>same sample, which did not react with TSSApep-II/V/VI, TSSApep-V/VI or chimeras.</p>c<p>these 9 samples also reacted with chimera TSSA-II/-I peptide.</p>d<p>same sample, which did not react with TSSApep-II/V/VI, TSSApep-V/VI or chimeras.</p>e<p>same sample.</p>f<p>same sample, which did not react with TSSApep-I, TSSApep-II/V/VI, TSSApep-V/VI or chimera TSSApep-II/-I.</p>g<p>non-specific binding; see text.</p>h<p>in each case the same sample reacted with TSSApep-III and TSSApep-IV.