Assessment of the effect of NAT treatment on SP immunoreactivity within the perivascular region following SCI.

<p>Ranking of SP immunoreactivity at 10(A) and 10 mm caudal (B) to the injury epicentre. Sham sections demonstrated moderate SP immunoreactivity (C). At both 5 and 24 hours post-SCI a slight decrease was observed within both segments of vehicle and NAT treatment groups. However at 3 days post-SCI NAT treated sections at both 10 mm rostral (E) and caudal (G) demonstrated a return to sham levels whilst vehicle treated remained reduced (D = 10 mm rostral; F = 10 mm caudal). *denotes p<0.05, **denotes p<0.01, ***denotes p<0.001, sham median ranking indicated by the dashed line. Scale bar = 25 µm.