Cell counts of oligodendrocytes, proliferating cells and microglia in the white matter seven days after 25 min of complete umbilical cord occlusion.

<p>Cell counts include total oligodendrocytes (Olig-2), immature/mature oligodendrocytes (CNPase), proliferating cells (Ki-67) and total microglial number (Iba-1) in the intragyral (panel A) and periventricular white matter (panel B). A significant increase in total numbers of oligodendrocytes was seen after occlusion-peptide compared to occlusion-vehicle in both the intragyral and periventricular white matter (<i>p</i>&lt;0.05). A significant reduction in numbers of immature/mature oligodendrocytes was seen in the occlusion-vehicle group compared to sham control, with an intermediate number in the occlusion-peptide group (<i>p</i>&lt;0.05). A significant increase in proliferation was seen in the occlusion-vehicle and occlusion-peptide groups compared to sham control with a further significant increase in the occlusion-peptide group compared to occlusion-vehicle (<i>p</i>&lt;0.05). A significant increase in total microglial number was seen in the occlusion-vehicle and occlusion-peptide groups compared to sham control (<i>p</i>&lt;0.05). *<i>p</i>&lt;0.05 compared to sham control. #<i>p</i>&lt;0.05 compared to the occlusion-vehicle group. Data are mean ± SEM.