Changes in gene expression between succeeding stages; transitions T1, T2 and T3.

<p>Differentially expressed genes (DEGs) are divided over three groups of absolute log2 fold changes in expression; 2 to 4 fold (orange), 4 to 8 fold (purple) or 8 or more fold (green). Genes with expression in only one of two compared stages (thus uniquely expressed in that particular comparison) predominantly show >8 fold changes and are additionally indicated between brackets within this group. Considerably more genes are up-regulated from BU to EG, whereas more genes are down-regulated from EG to EL. Numbers of up- and down-regulated genes from EL to MA are more balanced, although more genes are down- than up-regulated. In each transition, the largest number of DEGs is represented by the 2–4 fold group (orange). Relative high numbers of genes are completely turned off from EG to EL (135) and turned on from EL to MA (97).