Reduced ERG amplitudes in NaIO₃-treated αB crystallin knockout (αB-/-) mice.

<p>Three weeks after tail vein injection of 20/kg body weight NaIO₃, mesopic ERG responses were recorded in PBS-treated WT, NaIO₃-treated WT, PBS-treated αB-/-, and NaIO₃-treated αB-/- mice (representative ERGs shown in A). The amplitudes of <i>a</i> wave of the ERG of NaIO₃-treated αB-/- mice decreased by 68.3% compared with that of PBS-treated αB-/- mice (B). The amplitudes of <i>b</i> wave of the ERG of NaIO₃-treated αB-/- mice decreased by 55.3%, compared with that of PBS-treated αB-/- mice (C). Data are mean ± SEM, n = 5/group, *P<0.05, **P<0.01.