<p>(<b>A</b>) There was no significant difference in total insulin content between β-ARNT and floxed control islets one week post-transplantation (n = 6 per group). (<b>B</b>) The β-cell volume was not significantly different between the control and β-ARNT transplants (n = 6 per group). Data are presented as means ± SEMs. (<b>C</b>) Representative photomicrographs of kidney graft sections from control recipients and β-ARNT recipients (n = 4 mice/group). Brown coloration indicates insulin producing β-cells and blue is the haematoxylin counter stain.</p
<p>Representative anti-CXCL10/IP-10 stained graft-bearing kidney sections from normoglycemic untreat...
<div><p>(A) Glucose levels in durably grafted (E42 embryonic pancreas) and non-grafted alloxan-treat...
<p>Blood glucose levels (<b>A</b>) and body weight (<b>B</b>) of the animals (in percent) over the c...
<p>(<b>A</b>) β-ARNT donor mice had significant glucose intolerance compared to floxed controls and ...
<p>Insulin was stained in red to indicate the functional human islets after transplantation. Kidney ...
<p>(A) In control group (islets only), the expression of insulin became undetectable 7 days after tr...
<p>n = 8–13. * = p<0.05, t-test vs wild-type littermates of βIKK mice, n = 12–13.</p
<p>A. Average islet size per transplant. B. Blood glucose concentrations of STZ-induced diabetic mic...
<p>Blood glucose levels of C57Bl/6 mice with islet transplantation (A, n = 11 in vehicle control gro...
<p>NIT-1 or NIT–hAAT cells were transplanted into diabetic mice. After transplantation, the blood su...
<p>Insulin was stained in red to indicate the functional human islets after transplantation. vWF was...
<p>At day 130 after diabetes induction, pancreatic islets were observed (A) and quantified (B) in se...
<p>Upper row: insulin staining of CSPIO-labeled islet grafts; middle row: Prussian blue staining of ...
<div><p>Islet transplantation is a promising potential therapy for patients with type 1 diabetes. Th...
<p><b>A.</b> The recipient graft-bearing kidneys from normoglycemic untreated mice, and Dox- or Bort...
<p>Representative anti-CXCL10/IP-10 stained graft-bearing kidney sections from normoglycemic untreat...
<div><p>(A) Glucose levels in durably grafted (E42 embryonic pancreas) and non-grafted alloxan-treat...
<p>Blood glucose levels (<b>A</b>) and body weight (<b>B</b>) of the animals (in percent) over the c...
<p>(<b>A</b>) β-ARNT donor mice had significant glucose intolerance compared to floxed controls and ...
<p>Insulin was stained in red to indicate the functional human islets after transplantation. Kidney ...
<p>(A) In control group (islets only), the expression of insulin became undetectable 7 days after tr...
<p>n = 8–13. * = p<0.05, t-test vs wild-type littermates of βIKK mice, n = 12–13.</p
<p>A. Average islet size per transplant. B. Blood glucose concentrations of STZ-induced diabetic mic...
<p>Blood glucose levels of C57Bl/6 mice with islet transplantation (A, n = 11 in vehicle control gro...
<p>NIT-1 or NIT–hAAT cells were transplanted into diabetic mice. After transplantation, the blood su...
<p>Insulin was stained in red to indicate the functional human islets after transplantation. vWF was...
<p>At day 130 after diabetes induction, pancreatic islets were observed (A) and quantified (B) in se...
<p>Upper row: insulin staining of CSPIO-labeled islet grafts; middle row: Prussian blue staining of ...
<div><p>Islet transplantation is a promising potential therapy for patients with type 1 diabetes. Th...
<p><b>A.</b> The recipient graft-bearing kidneys from normoglycemic untreated mice, and Dox- or Bort...
<p>Representative anti-CXCL10/IP-10 stained graft-bearing kidney sections from normoglycemic untreat...
<div><p>(A) Glucose levels in durably grafted (E42 embryonic pancreas) and non-grafted alloxan-treat...
<p>Blood glucose levels (<b>A</b>) and body weight (<b>B</b>) of the animals (in percent) over the c...