Correlation between the increase of hemoglobin levels and baseline hemoglobin (a), CRP (b), reduction in the clinical disease activity index (c), and baseline LHD% (d).

<p>Dot plot suggests the correlation between (a) baseline hemoglobin (Hb) and ΔHb (N = 147), (b) baseline CRP and ΔHb (N = 147), and (c) reduction in the clinical disease activity index (ΔCDAI) and ΔHb (N = 122) in rheumatoid arthritis patients treated by TCZ (black closed square) or non-TCZ biologics (gray closed circle). The straight line corresponds to the best-fit linear regression line for all samples. (d) ΔHb levels in patients treated with TCZ (black closed square) or non-TCZ biologics (gray closed circle) are expressed in two groups divided by the baseline LHD% value 5.5. The straight lines represent the median levels of ΔHb for indicated groups. (ΔHb = Hb at week 12 - Hb at baseline, ΔCDAI = CDAI at baseline – CDAI at week 12; LHD% = low hemoglobin density.)