ACA infection alters susceptibility to EAE in mice primed with suboptimal doses of PLP 139–151.

<p>Groups of SJL mice were immunized with or without PLP 139–151 (2.5 or 10 µg/mouse) in CFA. On day 7 post-immunization, the animals were infected with ACA (1×10³) and the animals were monitored for clinical signs of EAE and scored. Data represent mean EAE scores for a group of mice pooled from two to three individual experiments.