Sox10 expressing cells in human temporal bones.

<p>Cells staining positively for Sox10 were seen in several locations of the human cochlea including the lateral wall (A, B), the organ of Corti (OCT; C) and the auditory nerve (AN; D). The images shown are of apical and middle turn sections from a 72 year-old (A–B) and a 91 year-old (C–E). Moderate to strong immunostaining for Sox10 was seen in marginal cells (A, arrows), intermediate cells (arrowhead) and presumed root cells underlying the spiral prominence epithelium (B, arrows) in a 72 year-old donor, whereas only a few cells with weak immunoreactivity for Sox10 were seen in the StV (arrowhead; an intermediate cell) and in the SP region (arrow) in the cochlea of a 91 year-old donor (E). E’–E” are enlarged images of the boxed area in E showing the staining pattern of Sox10⁺ marginal cell nuclei. Scale bars: 12 µm in A (applies to A–B’’); 12 µm in E (applies to C–E).