Differential expression of MYC, BCL-2 and p53 protein levels in aggressive DLBCL cell lines.

<p>(<b>A</b>) Western blotting analysis of concurrent c-Myc & Bcl-2 protein expression in U-2932, TMD-8, and Granta-519 cell lines in the absence and presence of MLN8237 (1.5 µM for 48 hr). The levels of p53 and BTK expression are evaluated <u>+</u> MLN8237. (<b>B</b>) Western blotting analysis of Bcl-2 protein expression in OCI-Ly10 cell line in the absence and presence of MLN8237 (1.5 µM for 48 hr).