Bcl6 deficiency decreases expression of lipogenic genes and proteins in liver.

<p><b>A</b>- Hepatic RNA was extracted from the liver of Bcl6 KO or WT mice, and expression of Fasn and Scd1 was measured by qpcr. Gene expression was calculated as fold change relative to WT mice. Bars show the mean+SE for 5 Bcl6 KO and 9 WT mice. <b>B</b> - Liver lysates were analyzed by immunoblotting using antibodies against FAS and SCD1 protein individually for 3 Bcl6 KO or 3 WT mice. α-tubulin served as a loading control. <b>C</b> - Quantification of immunoblots for FAS and SCD1 in B, normalized to α-tubulin, shown as mean+SE. Significant differences are designated by * (p<0.05), ** (p<0.005) and *** (p<0.0005).