Inhibition of cancer cell viability by different RE's in comparison with their major active components.

<p>Cell viability inhibition of cancer cells by different RE's and their equivalent concentrations of carnosic acid alone, carnosol alone, or both compounds in combination. SW620 colon and PANC-1 pancreatic cancer cells were treated with increasing concentrations of RE-2, RE-4 and RE-5, and the same concentrations of carnosic acid, carnosol, and the combination of both present in the RE's at each assayed condition. Extract ID and tumor cell line used in the assay are indicated in each graph. Results are shown as the mean ± SEM of three independent experiments, each performed in quadruplicate. Asterisks indicate statistically significant differences of carnosic acid or extract in comparison with the combination of carnosic acid and carnosol (U de Mann-Whitney; *p≤0.05; **p≤0.01). RE: supercritical rosemary extract.