<p>Serum IL-6 and TNF-alpha levels were measured by ELISA 6 h (A, B) or 24 h (C, D) after LPS challenge (n≥4 mice/group). *P<0.05 versus Sirt1<sup>+/+</sup>/LPS group.</p
Sirtuin 2 (SIRT2) and SIRT3 are cytoplasmic and mitochondrial NAD-dependent deacetylases. SIRT2 and ...
<p>Mice were <i>i</i>.<i>p</i>. injected with 1 μg S-LPS or R-LPS in 1 ml BSA-PBS and 90 min later s...
<p>(A), (B), and (C) IL-1<i>β</i>, TNF-α and MCP-1 levels in the plasma of apoE<sup>-/-</sup> mice w...
<p>Kidney tissues were harvested 6(n≥7 mice/group). Kidney samples were then subjected to immunoblot...
<p>ICAM-1 and VCAM-1expression were assayed 24 h after LPS challenge (n≥4 mice/group). (A, B) Repres...
<p>(A) <i>Sirt2</i> mRNA levels in <i>Sirt2<sup>+/+</sup></i> (+/+) and <i>Sirt2<sup>−/−</sup></i> (...
<p>Sirt1<sup>−/−</sup> mice and Sirt1<sup>+/+</sup> littermates were divided into four groups (Sirt1...
<p>Kidney tissues were harvested 6(n≥7 mice/group). Samples were subjected to immunoblotting assay. ...
<p>Twenty four hours after LPS challenge, kidney tissues from Sirt1<sup>−/−</sup> mice and sirt1<sup...
<p>Mice were challenged with LPS for 6 and 24 hr. (A) Real-time RT-PCR analysis of renal cytokine an...
Sepsis is a threatening health problem and characterized by microvascular dysfunction. In this study...
Bacterial endotoxin has been known to induce excessive inflammatory responses and acute kidney injur...
Bacterial endotoxin has been known to induce excessive inflammatory responses and acute kidney injur...
<p>The SIRT1 knockdown or control macrophages were treated with DHA (100 µM) for 24 hours and then t...
<p>(A) SIRT1 expression in peritoneal macrophages obtained from wild-type (WT) or myeloid-specific S...
Sirtuin 2 (SIRT2) and SIRT3 are cytoplasmic and mitochondrial NAD-dependent deacetylases. SIRT2 and ...
<p>Mice were <i>i</i>.<i>p</i>. injected with 1 μg S-LPS or R-LPS in 1 ml BSA-PBS and 90 min later s...
<p>(A), (B), and (C) IL-1<i>β</i>, TNF-α and MCP-1 levels in the plasma of apoE<sup>-/-</sup> mice w...
<p>Kidney tissues were harvested 6(n≥7 mice/group). Kidney samples were then subjected to immunoblot...
<p>ICAM-1 and VCAM-1expression were assayed 24 h after LPS challenge (n≥4 mice/group). (A, B) Repres...
<p>(A) <i>Sirt2</i> mRNA levels in <i>Sirt2<sup>+/+</sup></i> (+/+) and <i>Sirt2<sup>−/−</sup></i> (...
<p>Sirt1<sup>−/−</sup> mice and Sirt1<sup>+/+</sup> littermates were divided into four groups (Sirt1...
<p>Kidney tissues were harvested 6(n≥7 mice/group). Samples were subjected to immunoblotting assay. ...
<p>Twenty four hours after LPS challenge, kidney tissues from Sirt1<sup>−/−</sup> mice and sirt1<sup...
<p>Mice were challenged with LPS for 6 and 24 hr. (A) Real-time RT-PCR analysis of renal cytokine an...
Sepsis is a threatening health problem and characterized by microvascular dysfunction. In this study...
Bacterial endotoxin has been known to induce excessive inflammatory responses and acute kidney injur...
Bacterial endotoxin has been known to induce excessive inflammatory responses and acute kidney injur...
<p>The SIRT1 knockdown or control macrophages were treated with DHA (100 µM) for 24 hours and then t...
<p>(A) SIRT1 expression in peritoneal macrophages obtained from wild-type (WT) or myeloid-specific S...
Sirtuin 2 (SIRT2) and SIRT3 are cytoplasmic and mitochondrial NAD-dependent deacetylases. SIRT2 and ...
<p>Mice were <i>i</i>.<i>p</i>. injected with 1 μg S-LPS or R-LPS in 1 ml BSA-PBS and 90 min later s...
<p>(A), (B), and (C) IL-1<i>β</i>, TNF-α and MCP-1 levels in the plasma of apoE<sup>-/-</sup> mice w...
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