<p>Total iron content was determined by inductively-coupled plasma optical emission spectroscopy (ICP-OES). Statistical analysis performed by Student's paired t-test (*<i>p</i><0.05; ***<i>p</i><0.001, mean (µg Fe/mg wet tissue weight) ×100± SEM). Ages of mice: WT, 64–75 weeks; <i>Irp2<sup>−/−</sup></i>, 49–71 weeks.</p
<p>Iron levels were determined as described in <i>Methods</i>. Results are depicted graphically, wit...
<p>Representative images of BAL (bronchoalveolar lavages) cytospin slides obtained from WT and CFTR ...
<p>Livers and spleens from the Hjv−/− and wild type mice described in <a href="http://www.plosone.or...
<p>Female 4–5 week old mice were fed an iron deficient (2–6ppm iron) or control (200ppm iron) diet f...
<p>Semiquantification of iron deposits and collagen content in 15 month-old control, homo-βthal and ...
<p><b>A.</b> Hematology of 6–7 week old and 10–12 week old WT and Heph<sup>-/y</sup> male littermate...
*<p>indicates p≤0.05 for comparisons of unsupplemented vs. iron-supplemented diets.</p>**<p>Data sho...
<p>Plasma iron in µg/dL, non-heme tissue iron content in µg iron/g dry tissue.</p><p>(A) Female wild...
<p>(A–L), Perl’s DAB enhanced staining of the SN of WT mice at 15 weeks (A and B), 56 weeks (C and D...
<p>(A‒N) Perl’s DAB enhanced staining of the ST of WT mice at 15 weeks (A and B) and 56 weeks (C and...
<p>(A) WT and Zip14<sup>−/−</sup> mice were administered LPS (2 mg/kg or saline 0.5 mL; ip), 18 hr b...
Disorders of iron metabolism are a significant problem primarily in young and old populations. In th...
In blood serum: a) Total iron concentration; b) Transferrin saturation; c) Total concentration of se...
<p>Data are from two independent experiments and presented as mean ± SD (n = 6 mice per group).</p
<p>(A) Time course of liver and spleen non-heme iron concentrations after switching to an iron-defic...
<p>Iron levels were determined as described in <i>Methods</i>. Results are depicted graphically, wit...
<p>Representative images of BAL (bronchoalveolar lavages) cytospin slides obtained from WT and CFTR ...
<p>Livers and spleens from the Hjv−/− and wild type mice described in <a href="http://www.plosone.or...
<p>Female 4–5 week old mice were fed an iron deficient (2–6ppm iron) or control (200ppm iron) diet f...
<p>Semiquantification of iron deposits and collagen content in 15 month-old control, homo-βthal and ...
<p><b>A.</b> Hematology of 6–7 week old and 10–12 week old WT and Heph<sup>-/y</sup> male littermate...
*<p>indicates p≤0.05 for comparisons of unsupplemented vs. iron-supplemented diets.</p>**<p>Data sho...
<p>Plasma iron in µg/dL, non-heme tissue iron content in µg iron/g dry tissue.</p><p>(A) Female wild...
<p>(A–L), Perl’s DAB enhanced staining of the SN of WT mice at 15 weeks (A and B), 56 weeks (C and D...
<p>(A‒N) Perl’s DAB enhanced staining of the ST of WT mice at 15 weeks (A and B) and 56 weeks (C and...
<p>(A) WT and Zip14<sup>−/−</sup> mice were administered LPS (2 mg/kg or saline 0.5 mL; ip), 18 hr b...
Disorders of iron metabolism are a significant problem primarily in young and old populations. In th...
In blood serum: a) Total iron concentration; b) Transferrin saturation; c) Total concentration of se...
<p>Data are from two independent experiments and presented as mean ± SD (n = 6 mice per group).</p
<p>(A) Time course of liver and spleen non-heme iron concentrations after switching to an iron-defic...
<p>Iron levels were determined as described in <i>Methods</i>. Results are depicted graphically, wit...
<p>Representative images of BAL (bronchoalveolar lavages) cytospin slides obtained from WT and CFTR ...
<p>Livers and spleens from the Hjv−/− and wild type mice described in <a href="http://www.plosone.or...