The long lasting effects of corticosterone treatment on AHPs and action potential firing of layer 2/3 prelimbic pyramidal neurons.

<p><i>A</i>: locations of the recorded neurons on a pictorial coronal mouse brain section. <i>B</i>: representative AHP responses from vehicle and corticosterone groups overlaid with the fit. Light gray: raw trace, thick dark gray: fit, dotted line: mAHP decay, thin black line: sAHP decay. Inset shows the current protocol used to evoke the AHPs. <i>C</i>: traces of action potentials from neurons representative of the vehicle and corticosterone groups. Marking on the trace indicate the positions of spike amplitude, half-width and threshold measurements. <i>D</i>: mAHP peak amplitude averaged per group and per current step. <i>E</i>: averaged values of sAHP peak amplitude for each current injection step. <i>F</i>: accommodation index (% ratio of the interspike intervals of the last two spikes to the first two spikes) from vehicle and corticosterone groups. Number within brackets in the legends indicates number of neurons.