Changes in antibiotic use during the study period.

<p>AUD, antimicrobial use density; the number of defined daily doses per 1000 patient-days.</p><p>*<i>P</i>-values were determined using Kruskal-Wallis tests.</p>a,b,c<p>Same letters indicate statistical insignificance based on multiple comparisons performed using Bonferroni-corrected Mann-Whitney tests.